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Dr. Lorenz is a board-certified endocrinologist who comes to Kinexum from Portola Pharmaceuticals where he was Senior Vice President, Clinical Development and Scientific Licensing. At Portola, he developed the Phase 3 clinical program for betrixaban and initiated the international APEX clinical trial as well as consulting on the in-house programs for the andexanet alfa (a Factor Xa inhibitor antidote) and the proprietary Syk-JAK inhibitor. Prior to that, he served as Chief Medical Officer at Catalyst Biosciences, where he led strategic development plans in the areas of coagulation and transplant immunology. He has also served as Vice President at Johnson & Johnson Pharmaceutical Research Division where he led the Natrecor program and pursued in-licensing efforts with the cardiovascular business development group. He has held other senior positions in the biotechnology industry, including Chief Medical Officer at both Orexigen Therapeutics and at Corgentech, and Vice President of Medical Affairs at COR Therapeutics, where he was responsible for the clinical program for Integrilin. Dr. Lorenz has co-authored numerous scientific publications in peer-reviewed journals including JAMA, The Lancet, the New England Journal of Medicine, Circulation, Arthritis and Rheumatism, the Journal of the American College of Cardiology the Journal of Vascular Surgery and the American Heart Journal. He holds a B.A. in chemistry from Case Western Reserve University and an M.D. from Case Western Reserve University, School of Medicine. In addition to his services to Kinexum, Dr. Lorenz is a clinical development consultant to the SPARK program at Stanford University that provides interim funding for faculty projects that are candidates for out-licensing.
Services provided by Dr. Lorenz include: